Research Gone Astray
In the prestigious journal Nature, a research paper published in 2006 with 2273 citations pointed to a specific amyloid-β protein as being responsible for cognitive decline “independently of plaques or neuronal loss.” The journal states that it is investigating concerns.
Those concerns are described in more detail in the Science journal by a Neuroscientist and physician Matthew Schrag in Blots On a Field?
It was also addressed briefly in the Genetic Engineering & Biotechnology News article titled Questionable Data Jeopardizes Alzheimer’s Amyloid Theory.
Is it not troubling to think that research based on that study has led to potential treatments so off course that no breakthroughs have been made?
Mitochondrial Dysfunction
Dr. Linseman stated in a recent study that despite amyloid-β being widely recognized as a critical pathogenic player, the increasing evidence of neurotoxicity related to mitochondrial dysfunction causes hippocampal cell death.
The hippocampus plays a crucial role in memory formation in the brain. It is responsible for the creation of new memories and the retention of old ones. Without the hippocampus, no new memories can be formed, and future plans cannot be made. This is because the hippocampus acts as a sort of gateway between the short-term and long-term memory systems in the brain. It helps to consolidate memories and transfer them from short-term to long-term memory storage. The hippocampus also involves spatial navigation and other cognitive functions such as learning and emotion regulation. Overall, the hippocampus is a vital part of the brain that is essential for memory and cognitive functioning.
However, the damage may be a result rather than a cause.
Not All the Research is Bad
But why should we trust any of them? Really, I believe that integrity and honesty can shine through.
Interestingly, Daniel Goleman is an author and science journalist known for his books on emotional intelligence. In this article, the author mentions that Goleman described the contrast between the highly functional elderly nuns who donated their brains to science and the so-called tell-tale signs of Alzheimer's disease found in the cortical tissue, which contradicts the predominant (and now questionable) views.
Dr. Amen's opinion is significant because he is a highly respected neuroscientist and physician, and his PET brain scans are used to detect Alzheimer's disease and other neurological disorders. His disagreement with the Amyloid Theory suggests that other factors may contribute to Alzheimer's disease, and research should explore alternative explanations for the disease's development.is quite impressive with his groundbreaking PET brain scans and doesn’t believe in the Amyloid Theory either.
Get Help Today
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